Cannabis Bioavailability


The bioavailability of cannabis interaction with the human anatomy can vary dependent upon the method of consumption. Smoking flower through combustion of the dried plant material is the most common these days, with immediate effects. Edibles tend to last a bit longer but take a little while to kick in. Vaping can be similar to smoking, but reminds me of that 'creeper-like' effect that some strains tend to have, and can end up lasting for a little while. Topical products are even marketed as being non-psychoactive, especially if high in CBD and low in THC. As information and awareness about cannabis spreads, the methods of consumption of the cannabis plant can be more dialed in and simplified at the end product.

To understand what works best for you, it's always a good idea to get your own experience. Most of the time, we can look at cannabinoid ratios, terpenes and genetic lineage to assume the intended effects of a cannabis strain or product. As in, we usually ended up smoking what we liked smelling! Knowledge about terpenes was there 10 years ago (as they exist in plants beyond cannabis), but the information wasn't truly marketed alongside effects based products, until recently. Entire products, like all-in-one vaporizers are formulated around them.

With this information expansion more edibles, tinctures, topicals and ratio specific products are getting created. This would mean that a single strain could have varying degrees of effect on the user, depending on which product it was manufactured into. To understand it a bit better, check out the diagram below about cannabis bioavailability, dependent on the intake method.

In pharmacology, bioavailability is a subcategory of absorption and is the fraction of an administered dose of unchanged drug that reaches the systemic circulation, one of the principal pharmacokinetic properties of drugs. By definition, when a medication is administered intravenously, its bioavailability is 100% - Wikipedia.

Information referenced from Leafly and Zana Medical.

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